Joel N Blankson, Justin R Bailey
& Robert F Siliciano
Joel N. Blankson, Justin R. Bailey and Robert F. Siliciano are with the Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. rsilici1@jhmi.edu
Substitutions in CD8+ T cell epitopes in viral proteins can alter the complex interaction between viruses and host immunity. Reduced viral fitness and recognition of altered and subdominant epitopes are possible outcomes.
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