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News and Views
Nature Immunology 7, 121 - 122 (2006)
doi:10.1038/ni0206-121

Crosscurrents in HIV-1 evolution

Joel N Blankson, Justin R Bailey & Robert F Siliciano

Joel N. Blankson, Justin R. Bailey and Robert F. Siliciano are with the Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. rsilici1@jhmi.edu

Substitutions in CD8+ T cell epitopes in viral proteins can alter the complex interaction between viruses and host immunity. Reduced viral fitness and recognition of altered and subdominant epitopes are possible outcomes.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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