Nature Immunology
- 7, 1182 - 1190 (2006)
Published online: 8 October 2006; | doi:10.1038/ni1396
RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte developmentYi Gu, Hee-Don Chae, Jamie E Siefring, Aparna C Jasti, David A Hildeman & David A Williams Supplementary Fig. 1 (pdf 760K)
Gene-targeted deletion of the murine Rhoh allele. Supplementary Fig. 2 (pdf 340K)
Viability and proliferation of WT and Rhoh-/- thymocytes. Supplementary Fig. 3 (pdf 164K)
Thymic cellularity and distribution of CD4+CD8+ thymocyte subsets in p14tg/+ Rhoh-/- mice. Supplementary Fig. 4 (pdf 972K)
Impaired phosophorylation and recruitment of Zap70 to the immunological synapse in Rhoh-/- peripheral T cells. Supplementary Table 1 (pdf 88K)
T and B lymphocyte populations in Rhoh-/- mice. Supplementary Table 2 (pdf 88K)
Engraftment and T cell reconstitution of the RhoH-transduced Rhoh-/- BM cells in Rag2-/- recipient mice. Supplementary Methods (pdf 72K)
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