Nature Immunology
- 7, 1019 - 1021 (2006)
doi:10.1038/ni1006-1019
Passera ou ne passera pas—accessibility is keyJean-Pierre de Villartay
Jean-Pierre de Villartay is at INSERM, Hôpital Necker–Enfants Malades, U768 Unité Développement Normal et Pathologique du Système Immunitaire, Paris, F-75015 France, and at the Université Paris Descartes, Faculté de Médecine René Descartes, Paris, F-75005 France. devillar@necker.fr
Immunoglobulin and T cell receptor (TCR) germline transcription is associated with V(D)J recombination of these loci. New work formally demonstrates that transcriptional read-through of the TCR–J cluster indeed regulates TCR-J rearrangements.
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