Roman Dziarski is at the Indiana University School of Medicine, Northwest Campus, Gary, Indiana 46408, USA. rdziar@iun.edu
Yersinia pestis evades lipopolysaccharide (LPS)-induced inflammation and establishes deadly infection mediated by myriad virulence factors. Virulence can be completely neutralized, however, if Y. pestis expresses a Toll-like receptor 4–stimulating LPS.
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