Nature Immunology 7, 19 - 23 (2006)
Published online: 15 December 2005; | doi:10.1038/ni1296
HIV vaccine design: insights from live attenuated SIV vaccinesWayne C Koff1, Philip R Johnson2, David I Watkins3, Dennis R Burton4, Jeffrey D Lifson5, Kim J Hasenkrug6, Adrian B McDermott1, Alan Schultz1, Timothy J Zamb1, Rosanne Boyle1
& Ronald C Desrosiers71
Wayne C. Koff, Adrian B. McDermott, Alan Schultz, Timothy J. Zamb and Rosanne Boyle are with the International AIDS Vaccine Initiative, New York, New York 10038, USA. wkoff@iavi.org
2
Philip R. Johnson is with The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318, USA. 3
David I. Watkins is with the Wisconsin Primate Research Center and Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin 53706-1532, USA. 4
Dennis R. Burton is in the Departments of Immunology and Molecular Biology, Scripps Research Institute, La Jolla, California 92037, USA. 5
Jeffrey D. Lifson is with the Retroviral Pathogenesis Laboratory, AIDS Vaccine Program, Science Applications International Corporation Frederick, National Cancer Institute-Frederick, Frederick, Maryland 21702, USA. 6
Kim J Hasenkrug is in the Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA. 7
Ronald C. Desrosiers is with the Harvard Medical School New England Regional Primate Research Center, Southborough, Massachusetts 01772, USA. The International AIDS Vaccine Initiative has established a consortium to elucidate mechanisms of protection conferred by live attenuated simian immunodeficiency virus vaccines in monkeys. Here, the strategies defining key components of the protective immune response elicited by these vaccines are discussed.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|
