Fcγ receptor–mediated phagocytosis requires Rac and Cdc42 GTPases. New data show that CAPRI, a GTPase-activating protein for Ras, functions as an adaptor for Rac and Cdc42 during phagocytosis and early phases of bacterial immunity.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Cox, D. et al. J. Exp. Med. 186, 1487–1494 (1997).
Lockyer, P.J., Kupzig, S. & Cullen, P.J. Curr. Biol. 11, 981–986 (2001).
Zhang, J., Guo, J., Dzhagalov, I. & He, Y.-W. Nat. Immunol. 6, 911–919 (2005).
Patel, J.C., Hall, A. & Caron, E. Mol. Biol. Cell 13, 1215–1226 (2002).
Rossman, K.L., Der, C.J. & Sondek, J. Nat. Rev. Mol. Cell. Biol. 6, 167–180 (2005).
Liu, Q. et al. J. Cell Biol. 170, 183–190 (2005).
Minagawa, T., Fukuda, M. & Mikoshiba, K. Biochem. Biophys. Res. Commun. 288, 87–90 (2001).
Scott, C.C. et al. J. Cell Biol. 169, 139–149 (2005).
Di Virgilio, F., Meyer, B.C., Greenberg, S. & Silverstein, S.C. J. Cell Biol. 106, 657–666 (1988).
Park, D.J., Min, H.K. & Rhee, S.G. J. Biol. Chem. 267, 1496–1501 (1992).
Wen, R., Jou, S.T., Chen, Y., Hoffmeyer, A. & Wang, D. J. Immunol. 169, 6743–6752 (2002).
Dermardirossian, C. & Bokoch, G.M. Trends Cell Biol. 15, 356–363 (2005).
Scheffzek, K., Stephan, I., Jensen, O.N., Illenberger, D. & Gierschik, P. Nat. Struct. Biol. 7, 122–126 (2000).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Greenberg, S. A CAPRIciously translocating Rac adaptor. Nat Immunol 6, 864–866 (2005). https://doi.org/10.1038/ni0905-864
Issue Date:
DOI: https://doi.org/10.1038/ni0905-864