H. Robson MacDonald is at the Ludwig Institute for Cancer Research, Chemin des Boveresses 155, 1066 Epalinges, Switzerland.
Physiological tolerance of natural killer (NK) cells to self tissues is believed to require the expression of at least one inhibitory receptor specific for self MHC. This dogma may require revision with the identification of self-tolerant NK cells lacking self MHC−specific receptors.
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