Nature Immunology
6, 864 - 866 (2005)
doi:10.1038/ni0905-864
A CAPRIciously translocating Rac adaptorSteven Greenberg
Steven Greenberg is in the Departments of Medicine and Pharmacology, Columbia University, New York, New York 10032, USA. smg8@columbia.edu
Fc receptor−mediated phagocytosis requires Rac and Cdc42 GTPases. New data show that CAPRI, a GTPase-activating protein for Ras, functions as an adaptor for Rac and Cdc42 during phagocytosis and early phases of bacterial immunity.
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