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News and Views
Nature Immunology  6, 756 - 757 (2005)
doi:10.1038/ni0805-756

It takes nerve to dampen inflammation

Christine N Metz & Kevin J Tracey

Christine N. Metz and Kevin J. Tracey are with The Herman and Susan Merinoff Center for Patient Oriented Research at The Institute for Medical Research at North Shore-LIJ, Manhasset, New York 11021, USA. cmetz@nshs.edu

Stimulation of the vagus nerve via the alpha7 nicotinic acetylcholine receptor can dampen macrophage function. This anti-inflammatory pathway seems to signal through the Jak2-STAT3 pathway.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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