Nature Immunology
6, 754 - 756 (2005)
doi:10.1038/ni0805-754
CD1d antigen presentation: treats for NKT cellsDale I Godfrey1, James McCluskey1
& Jamie Rossjohn21
Dale I. Godfrey and James McCluskey are in the Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia. godfrey@unimelb.edu.au
2
Jamie Rossjohn is with The Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia. jamie.rossjohn@med.edu.au
Structural studies of CD1d presentation of  -galactosylceramide have shown that the lipid component fits snugly in the cleft, whereas the galactosyl head group protrudes upward, with key contact points between CD1d and the antigen conserved between mouse and human structures.
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