Nature Immunology
6, 751 - 752 (2005)
doi:10.1038/ni0805-751
GSK3: an in-Toll-erant protein kinase?James R Woodgett
& Pamela S Ohashi
James R. Woodgett is with the Ontario Cancer Institute, Toronto, Ontario M5G 2M9, Canada. Pamela S. Ohashi is with the Ontario Cancer Institute, Toronto, Ontario M5G 2M9, Canada and the Campbell Family Institute for Breast Cancer Research, Toronto, Ontario M5C 2M1, Canada. jwoodget@uhnres.utoronto.ca
Toll-like receptors are crucial in modulating immune responses. Glycogen synthase kinase 3 is involved in Toll-like receptor signaling and regulates the production of proinflammatory cytokines and septic shock.
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