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News and Views
Nature Immunology  6, 429 - 430 (2005)
doi:10.1038/ni0505-429

Integrin activation under flow: a local affair

Carlo Laudanna

Carlo Laudanna is in the Department of Pathology, University of Verona, Verona VR 37134, Italy. carlo.laudanna@univr.it

Chemokines 'trigger' the integrin LFA-1 to different conformational and affinity states. Elegant experiments provide new insights into the involvement of different LFA-1 affinity states in rapid lymphocyte arrest under flow.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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