Alain Trautmann is with the Institut Cochin, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, 75014 Paris, France. trautmann@cochin.inserm.fr
Chemokines not only act as chemotactic and chemokinetic molecules but also are inducers of integrin-dependent adhesion. Analysis of an immunological synapse now demonstrates an additional function for chemokines as costimulatory molecules.
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