Sten Eirik W. Jacobsen is with the Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, 221 84 Lund, Sweden. sten.jacobsen@stemcell.lu.se
Self-renewal of hematopoietic stem cells allows life-long production of blood cells. Notch signaling is critically involved in this process by maintaining a pool of self-renewing hematopoietic stem cells.
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