Abul K. Abbas is in the Department of Pathology, University of California San Francisco, San Francisco, California 94143, USA. Arlene H. Sharpe is in the Department of Pathology, Harvard Medical School and Brigham & Women's Hospital, Boston, Massachusetts 02115, USA. aabbas@itsa.ucsf.edu
Resting dendritic cells can induce T cell tolerance. This process requires engagement of the costimulatory molecules PD-1 and CTLA-4 on T cells.
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