Nature Immunology 6, 1245 - 1252 (2005)
Published online: 13 November 2005; | doi:10.1038/ni1271
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunityChen Zhu, Ana C Anderson, Anna Schubart, Huabao Xiong, Jaime Imitola, Samia J Khoury, Xin Xiao Zheng, Terry B Strom
& Vijay K Kuchroo Supplementary Table 1 (pdf 100K) The kinetics of galectin-9 induced cell death in TH1 and TH2 cells. Supplementary Video 1 (mov 1M) Galectin-9 induced cell aggregation and subsequent cell death in TH1 cells. DO11.10 TH1 cell aggregation began at 15 minutes after addition of 0.5 M Gal-9. Supplementary Video 2 (mov 512K) Galectin-9 induced cell aggregation and subsequent cell death in TH1 cells. DO11.10 TH1 cells form tight junctions 1 h after 0.5 M Gal-9 stimulation. Supplementary Video 3 (mov 700K) Galectin-9 induced cell aggregation and subsequent cell death in TH1 cells. Induction of cell death in the aggregated DO11.10 TH1 cells.
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