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Article
Nature Immunology 6, 1245 - 1252 (2005)
Published online: 13 November 2005; | doi:10.1038/ni1271

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

Chen Zhu, Ana C Anderson, Anna Schubart, Huabao Xiong, Jaime Imitola, Samia J Khoury, Xin Xiao Zheng, Terry B Strom & Vijay K Kuchroo

Supplementary Table 1 (pdf 100K)
The kinetics of galectin-9 induced cell death in TH1 and TH2 cells.

Supplementary Video 1 (mov 1M)
Galectin-9 induced cell aggregation and subsequent cell death in TH1 cells. DO11.10 TH1 cell aggregation began at 15 minutes after addition of 0.5 muM Gal-9.

Supplementary Video 2 (mov 512K)
Galectin-9 induced cell aggregation and subsequent cell death in TH1 cells. DO11.10 TH1 cells form tight junctions 1 h after 0.5 muM Gal-9 stimulation.

Supplementary Video 3 (mov 700K)
Galectin-9 induced cell aggregation and subsequent cell death in TH1 cells. Induction of cell death in the aggregated DO11.10 TH1 cells.


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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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