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News and Views
Nature Immunology 6, 1215 - 1216 (2005)
doi:10.1038/ni1205-1215

Signals for lymphocyte egress

Klaus Ley1 & Maggie Morris2

1  Klaus Ley is in the Departments of Biomedical Engineering, Molecular Physiology and Biological Physics and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908, USA. klausley@virginia.edu

2  Maggie Morris is in the Department of Biomedical Engineering and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908, USA.

Lymphocyte egress from lymph nodes is thought to require signals on T cells for the initiation of exit movement. Another possibility is that signaling instead opens endothelial 'gates' through which lymphocytes pass.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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