Nature Immunology 6, 1215 - 1216 (2005)
doi:10.1038/ni1205-1215
Signals for lymphocyte egressKlaus Ley1
& Maggie Morris21
Klaus Ley is in the Departments of Biomedical Engineering, Molecular Physiology and Biological Physics and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908, USA. klausley@virginia.edu
2
Maggie Morris is in the Department of Biomedical Engineering and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908, USA. Lymphocyte egress from lymph nodes is thought to require signals on T cells for the initiation of exit movement. Another possibility is that signaling instead opens endothelial 'gates' through which lymphocytes pass.
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