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Breaking down the barriers to cancer immunotherapy

Abstract

Emerging insights into the mechanisms of activation and negative regulation of innate and adaptive immune cells are providing new opportunities for the development of safe and effective cancer vaccines.

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Figure 1: Innate and adaptive immune cell mediated tumoricidal activities.
Figure 2: Opportunities for adaptive immunotherapy and cancer vaccines.

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Correspondence to Ellen Puré.

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Puré, E., Allison, J. & Schreiber, R. Breaking down the barriers to cancer immunotherapy. Nat Immunol 6, 1207–1210 (2005). https://doi.org/10.1038/ni1205-1207

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