Rodger P. McEver is with the Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA. rodger-mcever@omrf.ouhsc.edu
L-selectin expressed by lymphocytes interacts with specialized glycans on endothelium to mediate lymphocyte rolling. Two sulfotransferases that act cooperatively to add sulfate esters to a specific sugar residue on glycans are critical for this process.
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