Signaling negative selection: is MINK the missing link?
Ed Palmer
Ed Palmer is in the Laboratory of Transplantation Immunology and Nephrology, Department of Research, University Hospital Basel, Hebelstrasse 20, CH-4031 Basel, Switzerland. ed.palmer@unibas.ch
The signaling pathways distinguishing positive and negative thymic selection are critical for establishing T cell immunity and tolerance. The kinase MINK might be an important component that differentiates these two events.
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