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News and Views
Nature Immunology  5, 699 - 701 (2004)
doi:10.1038/ni0704-699

RIGging an antiviral defense—it's in the CARDs

David E Levy & Isabelle J Marié

David E. Levy is in the Departments of Pathology and Microbiology and Isabelle J. Marié is in the Department of Pathology, New York University School of Medicine, New York, New York 10016, USA. del243@med.nyu.edu

How do cells fend off intracellular viruses that slip in below extracellular defensive 'radar screens'? The identification of a cytoplasmic RNA helicase that signals through CARD interactions links viral detection to the interferon-beta induction pathway.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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