Dendritic cells: the immune information management experts
Tim R Mosmann
& Alexandra M Livingstone
Tim R. Mosmann and Alexandra M. Livingstone are at the David H. Smith Center for Vaccine Biology and Immunology, Aab Institute of Biomedical Sciences, and the Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York. tim_mosmann@urmc.rochester.edu
Dendritic cells sense and respond to multiple signals that are then conveyed to lymphocytes to direct appropriate immune responses. This flow of information is bidirectional, as antigen-experienced T cells also influence dendritic cell function.
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