Astar Winoto is in the Department of Molecular and Cell Biology, Division of Immunology, University of California, Berkeley, California 94720, USA. winoto@berkeley.edu
Human caspase-12, unlike that found in the mouse, is not involved in apoptosis and thus its physiological function is unclear. However, a unique polymorphism of human caspase-12 has demonstrated its importance in innate immunity.
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