Ellen V. Rothenberg is in the Division of Biology 156-29, California Institute of Technology, Pasadena, California
91125, USA. evroth@its.caltech.edu
Given the right sequence of cues, embryonic stem cells can develop into any cell type found in the body. New work shows how manipulation of supportive stromal cells to provide essential Delta-Notch interactions allows embryonic stem cells to develop into functional T lymphocytes during in vitro culture.
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