Matti Davis and Yinon Ben-Neriah are at the Lautenberg Center for Immunology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel. yinon@cc.huji.ac.il
Anergy induction initiates a transcription program involving the upregulation of several ubiquitin ligases (E3s). New data show how these E3s contribute to the establishment of anergy.
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