Having it both ways: MHC recognition in cis and trans
Paul J Leibson
& Larry R Pease
Paul J. Leibson and Larry R. Pease are in the Department of Immunology, Mayo Clinic College of Medicine, 200 First Street S.W., Rochester, Minnesota 55905, USA. leibson.paul@mayo.edu
Natural killer cells are kept in check by their inhibitory receptors. Data now indicate that these receptors can bind ligands that are next to them on the same cell surface, with unexpected functional consequences.
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