Amy L. Kenter and Palash Bhattacharya are in the Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, Illinois 60612-7344, USA. star1@uic.edu
Immunoglobulin class-switch recombination occurs in both frogs and mammals. A new study shows that the recognition mechanism used for the targeting of switch sequences might be evolutionary conserved.
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