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Nature Immunology  4, 652 - 654 (2003)
doi:10.1038/ni0703-652

Intracellular debugging

Koichi S Kobayashi, Elizabeth E Eynon & Richard A Flavell

Koichi S. Kobayashi, Elizabeth E. Eynon and Richard A. Flavell are in the Section of Immunobiology and Elizabeth E. Eynon and Richard A. Flavell are also in the Howard Hughes Medical Institute, Yale University School of Medicine, 300 Cedar Street, New Haven, Connecticut 06520-8011, USA. Richard.flavell@yale.edu

A family of intracellular molecules called NODs has been proposed to sense bacteria within the cell. New data now show that NOD1 senses a distinct bacterial component and may thus be important in responding to bacteria with this molecular signature.

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REVIEWS
Cell death and immunity: NODs: intracellular proteins involved in inflammation and apoptosis
Nature Reviews Immunology Review (01 May 2003)

RESEARCH
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
Nature Immunology Article (01 Jul 2003)
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
The EMBO Journal Article (07 Apr 2004)

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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