Manipulating hematopoietic stem cell amplification with Wnt
Connie J Eaves, PhD
Connie Eaves is in the Terry Fox Laboratory, British Columbia Cancer Agency and University of British Columbia, Vancouver, British Columbia, Canada. ceaves@bccancer.bc.ca
The mechanisms that regulate self-renewal of hematopoietic stem cells have remained elusive. Recent papers in Nature point to an important role of the Wnt−-catenin signaling pathway in promoting this process.
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