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Commentary
Nature Immunology  4, 425 - 428 (2003)
doi:10.1038/ni0503-425

Cellular versus humoral immunology: a century-long dispute

Arthur M. Silverstein

Institute of the History of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA. arts@jhmi.edu

Historical insight: Immunology's founding fathers argued fiercely about whether Metchnikoff's phagocytes or Ehrlich's antibodies were the most important mediators of immunity. Antibodies won out, but even after lymphocytes re-established cellular immunology, the humoralist-cellularist divide persisted.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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