Il2 transcription unleashed by active DNA demethylation
Adrian Bird
Wellcome Trust Centre for Cell Biology, Kings Buildings, Edinburgh University, Edinburgh EH9 3JR, UK. a.bird@ed.ac.uk
The idea that genes are transcriptionally activated by rapid CpG demethylation has been controversial. New data provides the most compelling evidence yet, implicating a mysterious enzyme activity that can actively demethylate DNA.
