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Journal home Advance online publication Current issue Archive Press releases Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Immunology Nature Medicine Nature Cell Biology NI Tutorial: Finding regulatory DNA regions Signaling Gateway Immunology & Cell Biology Mucosal Immunology Nature Conferences NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications Commentary Nature Immunology  4, 97 - 99 (2003) doi:10.1038/ni0203-97 Thymic output: a bad TREC record Mette D. Hazenberg1, José A.M. Borghans1, Rob J. de Boer2 & Frank Miedema1, 3 1  Department of Clinical Viro-Immunology, Sanquin Research at CLB and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. 2  Theoretical Biology, Utrecht University, Utrecht, The Netherlands. 3  Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Correspondence should be addressed to Frank Miedema fmiedema@sanquin.nlTREC assays are used to detect recent thymic emigrants and quantitate thymic output. However, the longevity of naive T cells combined with T cell division suggest TREC data should be interpreted with caution. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REFERENCE Acquired Immune Deficiency Syndrome (AIDS) Nature Encyclopaedia of Life Sciences  See all 3 matches for Reference NEWS AND VIEWS The impact of HIV on naïve T-cell homeostasis Nature Medicine News and Views (01 Sep 2000) Immunology: The thymus in the age of retirement Nature News and Views (17 Dec 1998)  See all 7 matches for News And Views  Top Abstract | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Direct Molecular Detection of Proteins and Nucleic Acids Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id... Optimizing Sub-cellular Localization Tags Deadline: Jan 31 2010 Reward: $20,000 USD The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression.... More Challenges Powered by: nature jobs Assistant Editor – Nature Immunology Nature Publishing Group New York, NY United States Post-doctoral Positions-Bioinformatics and Stem Cells Boston University School of Medicine Boston, Massachusetts, United States More science jobs Post a job for free Figures & Tables Export citation Search buyers guide:   ADVERTISEMENT

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