Division of Cellular Immunology, La Jolla Institute for Allergy & Immunology, San Diego, CA 92121, USA. michael@liai.org & doug@liai.org
Cellular parasites have evolved clever anti-apoptosis strategies to avoid being killed by CTLs. However, CTL release of granzyme A inactivates a key repair enzyme, Ape1, ensuring death of infected cells.
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