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Journal home Advance online publication Current issue Archive Press releases Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Immunology Nature Medicine Nature Cell Biology NI Tutorial: Finding regulatory DNA regions Signaling Gateway Immunology & Cell Biology Mucosal Immunology Nature Conferences NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Immunology  4, 101 - 103 (2003) doi:10.1038/ni0203-101 Everything is E(Z): linking histone methylation to B cell development Dale Ramsden & Yi Zhang Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA Correspondence should be addressed to Yi Zhang yi_zhang@med.unc.eduThe histone methyltransferases E(Z) and Ezh2 may control developmental fate by regulating homeobox gene expression. Emerging evidence suggests Ezh2 also plays a role in B cell development by controlling V(D)J recombination. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REVIEWS The establishment and maintenance of lymphocyte identity through gene silencing Nature Immunology Review (01 Jul 2003) NEWS AND VIEWS SET domain proteins reSET gene expression Nature Structural Biology News and Views (01 Dec 2002) Sounds of a silent Blimp-1 Nature Immunology News and Views (01 Mar 2004) RESEARCH Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement Nature Immunology Article (01 Feb 2003) EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer The EMBO Journal Article (15 Oct 2003)  See all 3 matches for Research  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Optimizing Sub-cellular Localization Tags Deadline: Jan 31 2010 Reward: $20,000 USD The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression.... Methods of Modeling Adaptation in Populations Deadline: Dec 30 2009 Reward: $15,000 USD The analysis of adaptation with a population is a frequently encountered computational modeling scen... More Challenges Powered by: nature jobs PhD - Helmholtz International Graduate School for Infection Research Helmholtz-Zentrum fur Infektionsforschung Braunschweig Germany Assistant Editor – Nature Immunology Nature Publishing Group New York, NY United States More science jobs Post a job for free Figures & Tables See also: Article by Su et al. Export citation Search buyers guide:   ADVERTISEMENT

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