 | About the cover
November 2003 - Vol 4 No 11
Nature Immunology 4 (2003)
| | |    | The lack of visible pigment combines with defective cytotoxic T lymphocytes (CTLs) in a rare form of albinism called Hermansky-Pudlak Syndrome type 2. Griffiths and colleagues (p 1111; News and Views on p 1049) found a particular AP-3 mutant that both missorts tyrosinase in melanocytes and disables lytic granule transport to the immune synapse. Photomicrograph of CTL granules (green) and microtubules (red); clay sculpture by Lewis Long.
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