Yoji Shimizu is at the Department of Laboratory Medicine and Pathology, Center for Immunology and Cancer Center, University of Minnesota Medical School, MMC 334/31, Church St. SE, Minneapolis, MN 55455. shimi002@umn.edu
The LFA-1 integrin is known to mediate adhesion between T cells and antigen-presenting cells. New evidence, however, is provided for its role in transmitting signals that promote T cell activation and differentiation.
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