Marsha Wills-Karp, Yasmine Belkaid
& Christopher L Karp
Marsha Wills-Karp, Yasmine Belkaid & Christopher L. Karp are in the Divisions of Immunobiology and Molecular Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45208, USA. wildc7@chmcc.org
Tim-3, a member of the T cell immunoglobulin mucin family, is expressed by TH1 cells. Analysis of Tim-3−Tim3 ligand signaling now shows this pathway is intimately involved in the counter-regulation of T helper type 1 immune responses.
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