Sebastian Amigorena is at the Institut Curie, U365 INSERM, 26 rue d'Ulm, 75005 Paris. sebas@curie.fr
The importance of cross-priming in vivo is controversial because its relative contribution in the presence of conventional priming is unclear. However, data from the examination of a conserved tyrosine residue in the cytoplasmic tail of MHC class I favor the cross-priming hypothesis.
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