 | About the cover
January 2003 - Vol 4 No 1
Nature Immunology 4 (2003)
| | |    | Prodding T cells to action involves turning on some molecules while reducing the activity of others. ZAP-70 is one of the first kinases to be activated. Mustelin and colleagues (page 44) report that the phosphatase VHR (red) is then recruited to lipid rafts (green) and phosphorylated by ZAP-70. Phospho-VHR then inactivates the MAP kinase pathway that involves Erk2. Immune synapse in acrylic on paper was painted by Michael Malicki.
|
|  |
|
