CD8+ T cell responses: it's all downhill after their prime ...
Joseph N. Blattman, Laurence E. Cheng
& Philip D. Greenberg
Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, 1100 Fairview Ave. N., PO Box 19028, Seattle, WA 98109, USA. pgreen@u.washington.edu
The resolution of an immune response was thought to coincide with the clearance of infection. However, the kinetics of CD8+ T cell decline may be programmed far before the antigen load lightens.