Class II peptide multimers: promise for type 1A diabetes?
George S. Eisenbarth1
& Gerald T. Nepom2
1
Barbara Davis Center for Childhood Diabetes, University of Colorado, Denver, Colorado 80262, USA. george.eisenbarth@uchsc.edu
2
Benaroya Research Institute, Seattle, Washington 98101, USA. nepom@vmresearch.org
Lack of proper tools hampers early diagnosis and treatment of antigen-specific autoimmune diseases. A new strategy that makes use of peptide-MHC reagents could control recent-onset diabetes in mice.