Nature Immunology
3, 318 - 321 (2002)
doi:10.1038/ni0402-318
Therapeutic applications for hematopoietic stem cell gene transferClaudio Bordignon
& Maria Grazia Roncarolo
HSR−Telethon Institute for Gene Therapy (TIGET) of Genetic Disease, Cancer Immunotherapy and Gene Therapy Program, Istituto Scientifico H.S. Raffaele, Universitá Vita-Salute San Raffaele, via Olgettina 58, 20132 Milan, Italy. claudio.bordignon@hsr.it
Transfer of genes into HSCs could be used to treat a variety of diseases from AIDS to cancer. Here Bordignon and Roncarolo discuss the logistics and progress of HSC gene transfer technology for the treatment of different diseases.
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