TS cells and immune tolerance induction: a regulatory renaissance?
Mark B. Feinberg
& Guido Silvestri
Emory University School of Medicine, Emory Vaccine Center, Atlanta, GA 30329, USA. mbf@sph.emory.edu
CD8+ TS cells induce antigen-specific tolerance. The TS cells may do this by increasing the expression of inhibitory receptor ILT3 and ILT4 on DCs, rendering these cells toleregenic to CD4 cells.