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Journal home Advance online publication Current issue Archive Press releases Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Immunology Nature Medicine Nature Cell Biology NI Tutorial: Finding regulatory DNA regions Signaling Gateway Immunology & Cell Biology Mucosal Immunology Nature Conferences NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Immunology  3, 1121 - 1122 (2002) doi:10.1038/ni1202-1121 The final cut: how ERAP1 trims MHC ligands to size Kirsten Falk & Olaf Rötzschke Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125 Berlin, Germany. falk@mdc-berlin.de or roetzsch@mdc-berlin.de Proteolytic cleavage generates the peptide repertoire displayed by MHC class I. Now, an interferon-−inducible aminopeptidase in the endoplasmic reticulum has been identified as the final player in this complex process.  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Novel Approaches to Protecting Maize from Insect Damage Deadline: Jan 31 2010 Reward: $20,000 USD The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re... Methods of Modeling Adaptation in Populations Deadline: Dec 30 2009 Reward: $15,000 USD The analysis of adaptation with a population is a frequently encountered computational modeling scen... More Challenges Powered by: nature jobs Faculty - Plant Cellular & Molecular Biology, Molecular Genetics & the Plant Molecular Biology / Biotechnology Program The Ohio State University Columbus, Ohio Scientist (Bioinformatics) Polyclone Bioservices Pvt. Ltd Bangalore India More science jobs Post a job for free Figures & Tables See also: Article by Saric et al. See also: Article by York et al. Export citation Search buyers guide:   ADVERTISEMENT

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