Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA. eLong@nih.gov
Receptors in the immune system usually specialize in transmitting specific types of signals. However, by associating with two different signaling subunits, the receptor NKG2D can transmit distinct signals for either costimulation or full-fledged activation.
