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Journal home Advance online publication Current issue Archive Press releases Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Immunology Nature Medicine Nature Cell Biology NI Tutorial: Finding regulatory DNA regions Signaling Gateway Immunology & Cell Biology Mucosal Immunology Nature Conferences NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Immunology  2, 581 - 582 (2001) doi:10.1038/89721 B cells with the guts to switch Edward A. Clark1, 2 & Kevin L. Otipoby1 1  Departments of Immunology and Microbiology, University of Washington, Seattle, WA 98195, USA. 2  eclark@bart.rprc.washington.edu Expression of mIgM was thought to be essential for the differentiation of B cells expressing antibodies of other classes. New evidence suggests isotype class switching to IgA can occur in the absence of mIgM.  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Optimizing Sub-cellular Localization Tags Deadline: Nov 29 2009 Reward: $20,000 USD The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression.... Single-cell Analysis Platform Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is... More Challenges Powered by: nature jobs Professor / Associate Professor (Pharmaceutics / Pharmaceutical Analysis&quality Control) Alliance Institute of Advanced Pharmacy and Health Sciences Hyderabad 500038 India PhD - Helmholtz International Graduate School for Infection Research Helmholtz-Zentrum fur Infektionsforschung Braunschweig Germany More science jobs Post a job for free Figures & Tables See also: Article by Macpherson et al. Export citation Search buyers guide:   ADVERTISEMENT

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