Department of Microbiology and Immunology and Hooper Foundation, HSW 1501, UCSF, San Francisco, CA 94143-0552, USA. (defranco@socrates.ucsf.edu)
Genetic ablation experiments have shown that Vav is critical for TCR signaling. Evidence is now emerging that the Vav family of signaling molecules play a critical role in antigen receptor signaling in B cells as well as in T cells.
