PKC-(I): the whole ignition system or just a sparkplug for T cell migration?
Ulrich H. von Andrian
The Center for Blood Research, Harvard Medical School, 200 Longwood Ave., Boston, MA 02115, USA. (uva@cbr.med.harvard.edu)
The events that enable polarization of T cells and migration across the vasculature to the target are largely unknown. New evidence suggests that PKC-(I) may be pivotal in controlling this process.