Nature Immunology
2, 288 - 290 (2001)
doi:10.1038/86292
Periscope, up! Monitoring microbes in the intestineAndrew T. Gewirtz
& James L. Madara
Department of Pathology, Emory University, WMB 2315, 1639 Pierce Drive, Atlanta, GA 30322, USA. (agewirt@emory.edu) Dendritic cells below the epithelium layer are now reported to send processes in between epithelial cells, while maintaining the integrity of the tight junctions. This mechanism could sample intestinal fluids for pathogens to aid immunologic protection of the host.
|