1
Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
2
Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.rac1@cornell.edu
New data shows that NADPH oxidase activation by Rac2 involves an insert-dependent interaction between Rac2 and cyt b. This unique activation mechanism has far-reaching implications for the regulation of related signaling systems.