Nature Immunology
2, 194 - 196 (2001)
doi:10.1038/85240
Rac inserts its way into the immune responseGregory R. Hoffman1
& Richard A. Cerione1, 21
Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA. 2
Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.rac1@cornell.edu
New data shows that NADPH oxidase activation by Rac2 involves an insert-dependent interaction between Rac2 and cyt b. This unique activation mechanism has far-reaching implications for the regulation of related signaling systems.
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